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This presentation involved initial thyrotoxicosis (excess thyroid hormone) followed by transient hypothyroidism (insufficient thyroid hormone), a pattern characteristic of destructive thyroiditis where inflammation damages thyroid tissue and releases stored hormones
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In a pooled analysis of data from STEP-HFpEF, STEP-HFpEF DM, FLOW and SELECT, all funded by Novo Nordisk, researchers observed semaglutide 1 mg or 2.4 mg reduced risk for worsening HF events and CV death compared with placebo
