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However, “the evidence is still evolving related to how these medications may impact complications related to obesity such as heart disease and diabetes.” The Pharmaceutical Strategies Group (PSG), a pharmaceutical management consulting company, surveyed 180 benefits executives representing health plans, employers and unions and found that these drugs are a major concern
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Serious adverse effects requiring monitoring include: Hypoglycemia : While GLP-1 receptor agonists have low intrinsic hypoglycemia risk due to glucose-dependent mechanisms, risk increases with concomitant insulin or sulfonylurea use
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