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While some trials show no major changes in BMD, others suggest slight improvements in bone turnover markers: Trials of liraglutide and exenatide generally show stable BMD over 6–12 months Certain populations — such as postmenopausal women or individuals with rapid weight loss — may show changes in bone markers like osteocalcin and P1NP However, most of these studies are small, short-term, or not powered for skeletal endpoints

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[DOI] [PubMed] [Google Scholar] [35].Singh B, Mahajan S, Abdella S, Khan R, Garg S