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Good indicators you're ready to stack: You've found your stable Reta dose (typically 1-3mg weekly) GLP-1 side effects have subsided or are manageable Weight loss or body comp changes are proceeding as expected You want to accelerate visceral fat loss or improve training performance The Stacking Order: Tesamorelin First If you're adding both compounds, start with Tesamorelin: Week 1-2: Add Tesamorelin 1mg daily (evening injection, before bed) Week 3-4: Increase to 2mg daily if tolerated Week 5-6: Add MOTS-C 500mcg daily (morning, any time) Why Tesamorelin First Synergy with Reta's fat loss mechanisms

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However, if you are sensitive to needle insertion, upgrading to 31G or 32G provides noticeably more comfort