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However, as proposed in the new CBT for BED approach, these medications may be suitable for patients with BED associated with clinical obesity without an overvaluation of shape and weight, without a history of anorexia nervosa or bulimia nervosa, and other severe, unstable mental disorders, who have successfully adopted a regular eating pattern and significantly reduced binge-eating episodes
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79 In addition to enhancing nitric oxide generation, GLP-1RAs exhibit both anti-apoptotic and anti-inflammatory effects
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