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Below is a general compounded semaglutide dosage progression, but individual needs may vary based on tolerance, weight loss goals, and healthcare provider recommendations
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A 2023 real-world evidence study (Blonde et al., Postgraduate Medicine 2023) found that patients with obesity who stayed at tirzepatide 5 mg for 12 months lost an average of 13.8% of baseline body weight, which exceeds the FDA's threshold for clinical significance (5%) by a wide margin
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