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A landmark phase 2 randomised controlled trial published in The Lancet in 2017 investigated exenatide in patients with moderate Parkinson's disease

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“This information is crucial for us to provide appropriate recommendations, such as adjusting drug administration before elective procedures, recommending extended fasting, or rescheduling an elective procedure if necessary.” The authors noted that in June, 2023, the American Society of Anesthesiologists issued new suggestions to physicians for evaluating GLP-1 RA use before surgery, and for informing patients about related risks of adverse outcomes