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After several hours, LPS treatment causes elevated IL-6 levels and hypoglycemia to develop and Ex4 administration blunts this hypoglycemic effect in rats suggesting that the effect of GLP-1 is related to glucose control (247) although the direction goes opposite of what we normally think of as GLP-1-mediated glucose control
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GLP-1 receptor agonists have transformed the treatment of obesity and Type 2 diabetes, but this breakthrough is the result of decades of scientific innovation and collaboration