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513 Studies suggest that the anti-inflammatory and metabolic effects of GLP-1RAs might also influence the progression of liver diseases, including HCC
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The key difference: glucagon alone would raise blood glucose, but Retatrutide's simultaneous GLP-1 activation produces enough insulin secretion to offset glucagon's glucose-raising effect, allowing the metabolic benefits of glucagon receptor activation (lipolysis, energy expenditure, hepatic lipid mobilization) to contribute to net metabolic improvement without compromising glycemic control
