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But heavy drinking can increase the risk of nausea, which is already a common side effect of GLP-1 medications

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Beyond weight outcomes, the Phase 2 obesity trial also reported improvements in several cardiometabolic markers, including: Reductions in waist circumference Improvements in fasting glucose and insulin sensitivity Favourable changes in blood pressure and lipid profiles Phase 3 trials — understood to form part of the TRIUMPH programme — are now underway, evaluating retatrutide in broader populations including people with type 2 diabetes and cardiovascular disease