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In theory, this could lead to greater fat loss, improved energy levels, and fewer metabolic side effects compared to tirzepatide alone
![Metformin and Tirzepatide in Lipedema: Targeting Fibrosis and Inflammation Through Complementary Pathways. A Mechanistic, Translational and Therapeutic Perspective[v1]](https://www.preprints.org/frontend/picture/ms_xml/manuscript/980d8a7dfcb6a99ac3ed5e654e3d6ea4/preprints-209856-g002.png)
