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While these data are astounding—with yearly progress in efficacy, we should consider that around 9% of patients receiving these game-changer treatments (Killworth, 2021) were not able to lose even 5% of their body mass over 72 weeks, and some trials are still struggling to get participants’ HbA1c below 7% (Table 1)
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doi: 10.1152/physrev.00034.2006 88 HunterK.HolscherC