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Potential Risks of Deviating From Standard Dosing Taking semaglutide twice per week at half-doses—or at full doses—introduces several unpredictable variables

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Why This Matters for Side Effects Gastrointestinal side effects such as nausea, vomiting, and diarrhea are common with both oral and injectable GLP-1 medications, occurring at rates similar across formulations and generally described as mild to moderate.⁴ Starting at lower doses and titrating carefully, as Whoosh's protocols are designed to do, is one of the most effective ways to minimize these effects while still achieving meaningful weight loss