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A GLP-1R agonist/GIPR antagonist peptide is theoretically possible but few full-length GIP-like antagonists were reported, 60 therefore it requires an array of attempts, at least an alanine-scan experiment of GIP with measuring of affinity
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Glucagon-like peptide-1 contributes to increases ABCA1 expression by downregulating miR-758 to regulate cholesterol homeostasis