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* Seguimiento médico regular: Es crucial un seguimiento médico continuo para evaluar la eficacia del tratamiento, ajustar la dosis si es necesario, y controlar cualquier posible efecto secundario a largo plazo

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This point is effectively made in a recently conducted large trial, which states that, “our understanding of the mechanisms of cardiovascular protection with [the GLP-1 agonist] semaglutide remains speculative…clinical benefit is [thought to be] achieved through multiple interrelated pathways.” Acknowledgement of this evidence gap prompted our lab, through use of a large animal model of CAD that replicates the features of disease as it occurs in humans, to investigate the cardiac consequences of semaglutide administration