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The OASIS-1 trial (Knop et al., Lancet 2023) showed: Mean weight loss of 15.1% at 50 mg over 68 weeks Mean weight loss of 11.4% at 25 mg Comparable safety to injectable semaglutide The 50 mg oral dose roughly matches the weight loss of injectable Wegovy 2.4 mg

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Other people experience heartburn, gas, or stomach heaviness