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In SUSTAIN-6, wherein semaglutide (subcutaneous injection) was administered at 0.5 or 1 mg per week, MACE was also reduced by 26% in the semaglutide group compared with the placebo group (HR 0.74, 95% CI 0.58–0.95) as was stroke (HR 0.61, 95% CI 0.38–0.99) [17]