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However, GLP-1 can act as a helpful addition — especially for patients who: Have obesity or are overweight Have type 2 diabetes or metabolic syndrome Need improvements in multiple metabolic risk factors (not just cholesterol) Who Benefits Most The cholesterol and lipid benefits of GLP-1 tend to be greater in: People who lose significant weight on it Those with elevated triglycerides to start Patients with insulin resistance or type 2 diabetes Individuals implementing lifestyle changes (diet, physical activity, etc.) alongside medication What to Expect & Important Things to Know Timeframe : Changes in lipid levels usually show up over months — not immediately

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It’s not clear whether the variants affect weight loss from these drugs, such as Ozempic and Wegovy, which are increasingly prescribed to treat obesity