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Substance use disorders (SUD) are quite common, with an estimated 46.3 million Americans over age 12 meeting DSM-5 criteria for an SUD, with 29.5 million of that group meeting the criteria for AUD
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Dipeptidyl peptidase 4 cleaves the penultimate prolines or alanines of peptides' N-terminal regions, such as GIP and GLP, effectively inactivating these peptides
