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Exenatide has a Pronounced Effect on Energy Intake but not Energy Expenditure in Non-Diabetic Subjects with Obesity: A Randomized, Double-blind, Placebo-Controlled Trial

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You are unlikely to see any positive impact if you use the medicine for less than three months, and we often recommend patients stay on them for 12-24 months to increase the likelihood of sustained weight loss.” Taking the medicine for the long-term helps cement healthier habits – eating less, exercising more – that increase the odds for permanent improvement after getting off the medicine