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What matters as much as the number is the method it was measured under: a 2.5 µm C18 column with mobile phase B held between 48% and 52% across 25 minutes
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Both Use Gradual Dosing, But Tirzepatide Offers More Flexibility Semaglutide uses a fixed, step‑up approach: Treatment begins with a low starting dose, which is gradually increased over several weeks
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