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In line with our findings of retigabine rescue in KO mice, several recent studies found that this Kv7-targeting agonist showed efficacy in ASD-relevant models [44, 45]: in Ank2 cKO mice, retigabine rescued cortical hyperexcitability and juvenile seizure-related mortality, and in Fmr1 -KO hippocampus, retigabine normalized CA1 excitability and abolished seizure-like events
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