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The technical reason for the long half-life is albumin binding via a C20 fatty diacid attachment

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Paquete:90 tabletas de 3 mg - Genérico

The first replaces the amino acid alanine at position 8 with 2-aminoisobutyric acid (Aib), making the molecule resistant to cleavage by the enzyme dipeptidyl peptidase-4 (DPP-4), which rapidly inactivates natural GLP-1