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For the majority of users who experienced fewer cravings, the change came quickly: 77% noticed the shift within the first month of starting GLP-1 medication

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In the STEP-1 trial, participants taking semaglutide 2.4 mg weekly (Wegovy) lost an average of 14.9% of their body weight over 68 weeks, with significant reductions in waist circumference averaging 13.5 cm (about 5.3 inches)