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Similar caution applies to more recent short-term combination studies reporting improvements in ovulation, endocrine markers, or related reproductive parameters, because endpoint definitions, denominators, concomitant therapies, and follow-up windows varied across trials (103, 104)
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* Based on the average weight loss in three 68-week clinical trials of patients without diabetes who reached and maintained a dose of 2.4 mg/week of GLP-1 treatment, along with a reduced- calorie diet and increased physical activity
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