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Symptoms worth watching for If you’ve been stable on levothyroxine for many years and start Wegovy, these symptoms suggest your thyroid levels may have changed: Returning fatigue, feeling colder, constipation, or low mood, which can mean your levels have dropped A racing heart, anxiety, tremor, sweating, or trouble sleeping, which can mean your levels are too high, sometimes after weight loss has reduced how much levothyroxine you need None of these is an emergency on their own, but they’re worth mentioning to your GP
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