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Table 1 from Glucagon-Like Peptide-1 (GLP-1) Receptor Agonists Drug Class Review | Semantic Scholar

De Araujo is finding that adverse reactions might be caused by how the drug differs from the naturally occurring peptide hormone: The hormone acts mostly locally and degrades quickly, while the medicine works mainly on the brain and is designed to stick around in the body

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These studies tracked thousands of participants over several years and focused on heart attacks, strokes, and cardiovascular mortality—conditions where clotting plays a central role

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