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GLP-1RAs Versus SGLT2is The aggregate crude incidence of thyroid tumors ranged from 0.88 (95% CI 0.82–0.94) to 1.00 (0.89–1.13) per 1,000 person-years in patients initiating GLP-1RAs and 0.82 (0.79–0.86) to 0.94 (0.86–1.02) per 1,000 person-years in patients initiating SGLT2is (Table 2)