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Was als Mittel zur Blutzuckersenkung entwickelt wurde, entpuppt sich als Pleiotropie-Meister mit organprotektiven Eigenschaften, die weit über den Stoffwechsel hinausgehen
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In addition, exendin-4 injection enhanced calcium signals in DMH GLP-1R neurons in the pre-ingestive stage, and exendin-4-induced pre-ingestive satiation was mitigated by optogenetic inhibition of DMH GLP-1R neurons
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