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Similar findings were reported in studies examining the pharmacokinetics, pharmacodynamics, and safety of RG7697/NNC0090-2746 in 56 patients with T2D who received once-daily subcutaneous injections of 0.25, 0.75, 1.1, 1.5, 2, or 2.5 mg of the co-agonist or placebo for 2 weeks in a randomized, double-blind, dose-escalation study [81]