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These highlights do not include all the information needed to use DUPIXENT safely and effectively. See full prescribing information for DUPIXENT. DUPIXENT® (dupilumab) injection, for subcutaneous useInitial U.S. Approval: 2017

More broadly, this reflects a larger issue that obesity is a chronic and complex disease, and we need to do a better job ensuring consistent access to evidence-based therapies

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Therefore, we conclude our crystal structure represents a physiologically relevant snapshot of GLP-1R in an inactive peptide-free state