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GLP-1R agonists ameliorate peripheral nerve dysfunction and inflammation via p38 MAPK/NF-κB signaling pathways in streptozotocin-induced diabetic rats

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The incretin hormone glucagon-like peptide-1 (GLP-1) is secreted from the intestinal L cells in response to the nutrient ingestion and potentiates glucose-dependent insulin secretion in healthy individuals 1,2