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Baseline assessment Before starting tirzepatide, consider a baseline abdominal ultrasound if you have any of these risk factors: Female sex plus age over 40 BMI over 40 Family history of gallstones History of rapid weight cycling Hispanic or Native American ethnicity History of biliary symptoms A baseline ultrasound establishes whether stones are already present before treatment begins
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The First Generation: GLP-1 Mono-Agonists The first major breakthrough was Exenatide (Byetta), followed by Liraglutide (Saxenda)
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