semaglutide fontana Semaglutide: Injection Home Kit – NativeMed badge_Bestseller Retatrutide — Oxford Research Size and Gauge:30 Gauge, 0.3 mL, 5/16-inch

semaglutide fontana Semaglutide: Injection Home Kit – NativeMed badge_Bestseller Retatrutide — Oxford Research Size and Gauge:30 Gauge, 0.3 mL, 5/16-inch

Retatrutide — Oxford Research Peptides

Endocrinology and Metabolism 304E222–E228

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Size and Gauge:30 Gauge, 0.3 mL, 5/16-inch

Check out this review article that does a great job summarizing and synthesizing the data so far 👉Amini 2025, No association: Abbass 2025, TriNetX: Chou 2025, TriNetX: Silverii 2024, meta-analysis of RCTs: Maro 2024, Sentinel: 🚨 Increased association between semaglutide and NAION: Hathaway 2024: Simonsen 2024: Grausland 2024: My synthesis 👇 Takeaways: 👉Pathophys seems to be related to vasodilation due to glucose control, leading to venous congestion, capillary leak, and edema ("compartment syndrome") 👉Most data is on semaglutide, not tirzepatide, but presumed pathophys applies to the drug class 👉Type 2 diabetes, OSA, and "disc at risk" status are additional risk factors 👉Data is inconsistent on whether risk of NAION is increased for people taking #GLP1s for #obesity My clinical practice: 👉For people with obesity, I'm paying attention but I'm not concerned 👉For people with #diabetes, I'm careful to avoid rapid glucose correction and I ask their ophthalmologist to comment whether patient has a "disc-at-risk" (ie, small optic disc to cup ratio)