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In the SURMOUNT-1 trial, participants taking tirzepatide at the 15 mg dose lost an average of 20.9% of their body weight over 72 weeks
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Regardless, constipation can contribute to UTIs, and it is well known that both GLP-1 and GLP-1/GIPs, such as tirzepatide, cause decreased GI motility as one of the ways they assist in weight reduction
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