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While a guest on the "Club Shay Shay" podcast, Iglesias explained why he ditched the GLP-1 that seemed to be working: "The problem with Ozempic is you're going to lose more muscle than fat." A 2024 review in Diabetes, Obesity, and Metabolism supports his assertion to an extent, stating that studies show GLP-1 use may cause the loss of up to 60% of a person's total lean muscle
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