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One of the most common questions I hear in my endocrinology clinic is: “Which is cheaper: Mounjaro, Ozempic, or generic semaglutide?” The answer depends on your goals, budget, diabetes status, and expected weight loss

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Therefore, the findings of the benefits of oral semaglutide regardless of SGLT2 inhibitor or MRA use among SOUL participants are clinically meaningful, highlighting the potential benefit for adding a GLP-1 RA to these therapies in people with T2D, ASCVD and/or CKD, and HF