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Therefore, while these data indicate a possible correlation, they do not confirm a causal relationship, and further studies are needed to clarify this potential link [2]
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In this context, murine studies have shown that sweet taste receptors (TAS1R2 and TAS1R3) are predominantly expressed in the hypothalamus and brainstem, whereas bitter receptors (TAS2R116, TAS2R118, TAS2R138, TAS2R104) are mainly expressed in the arcuate nucleus, ventromedial hypothalamus, dorsomedial hypothalamus, and nucleus of the solitary tract (120, 121)
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