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Adding to what we know about GLP-1 medications and colorectal cancer risk, Cuomo is the lead author of a new study recently published in the journal Cancer Investigation, which found that GLP-1 medications may help lower mortality risk for people who have colon cancer, a type of colorectal cancer
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The increase in cAMP levels in δ-cells is a consequence of GLP-1R activation in these cells, which in turn enhances the secretion of growth inhibitory hormone through signaling pathways such as PKA and Calcium/Calmodulin-dependent protein kinase (Brereton et al., 2015)
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