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The Vascular Hypometabolism Hypothesis: Reframing Dementia as an Energy and Delivery Problem A growing body of evidence suggests that dementia and Alzheimer’s disease are driven less by isolated protein aggregates and more by a chronic failure of blood flow, nutrient delivery, and metabolic precision in the brain, a framework often described as the vascular hypometabolism hypothesis [4, 5]
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The US market is big but complex Novo Nordisk holds patents on semaglutide in the US until 2032
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