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Additionally, in phase 2 studies in people with MASH and liver fibrosis, survodutide not only significantly improved liver steatosis, but also led to histologic improvement of MASH without worsening fibrosis in 43–62% of participants, versus 14% with placebo [41]
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As a single-site analysis of a self-enrolled commercial cohort, the population may not fully represent the broader diversity of individuals with obesity, particularly those with limited access to digital tools or private care settings
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