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The interventions reviewed were long-term therapies using GLP-1 receptor agonists, including semaglutide, liraglutide, tirzepatide, and exenatide, administered for a minimum of 40 weeks
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More recent agents include dual agonists such as tirzepatide, which activates both GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) receptors and produces even greater weight loss
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