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2021 ESC guidelines for the diagnosis and treatment of acute and chronic heart failure: developed by the task force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC) with the special contribution of the Heart Failure Association (HFA) of the ESC

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Furthermore, numerous research studies have shown that long-term blockade of GLP-1R signaling by GLP-1R antagonist exenatide- (9–39) enhances SBP but doesn’t affect DBP in normotensive and hypertensive rats, suggesting the relatively weak correlation between GLP-1 and DBP (99)

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