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To address confounding, the analysis adjusted for age, sex, obesity, smoking status, asthma, gastroesophageal reflux disease, ACE-inhibitor use, and baseline respiratory conditions using multivariable models and propensity score matching

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Significant vomiting or diarrhoea can lead to dehydration , which may increase the risk of acute kidney injury, particularly in older adults or those taking diuretics or other nephrotoxic medicines