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However, the definitive Exenatide-PD3 phase 3 trial , published in The Lancet in February 2025, found no disease-modifying benefit – exenatide did not slow Parkinson’s progression over 96 weeks compared to placebo in 194 patients ( [25] )
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[DOI] [PMC free article] [PubMed] [Google Scholar] 98.Kim S, Jung J, Kim H, Heo RW, Yi CO, Lee JE