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Different from HbA1c, in terms of weight loss, other GLP-1RAs had better weight loss effect except PEX168 100ug [0.49 kg (95% CI: −0.47, 1.46 kg)] was not as effective as placebo
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The class has produced the largest weight-reduction results ever reported in metabolic drug trials, and the pipeline of second- and third-generation molecules is now some of the most closely watched research in endocrinology