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The surprise factor is real: You might not ovulate for the first 1-2 months on GLP-1s, but then suddenly at month 3-4, everything “turns on.” You ovulate without realizing it, and pregnancy occurs before you’ve adapted to your new fertility status
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In the mechanism study, Ex-4 treatment significantly increased the expression of GLP-1R, p-AMPK, IκB-α, Occludin, and Claudin-5, while the expression of p-nuclear factor-kappa B (NF-κB) p65, matrix metalloproteinase-9 (MMP-9), and albumin was significantly decreased
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