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Purification of GLP-1R–PF-06372222–Fab7F38 complex The 1 L cell biomass expressing modified GLP-1R construct was lysed in a low salt buffer containing 10 mM HEPES pH 7.5, 20 mM KCl, 10 mM MgCl 2 , and EDTA-free protease inhibitor cocktail tablets
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These combination products simplify treatment by reducing injection burden while providing the benefits of both drug classes
