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The successful translation of GLP-1 science from bench to bedside reflects a body of work that is highly reproducible and based on mechanistic studies, which inform the design and rationale use of GLP-1–based therapies

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In our previous study [34] validating and describing this paradigm, we found a palatability-driven anticipation effect: S1 food consumption in the two-session paradigm strongly decreased in the b S1 v S2 condition in anticipation of the more palatable S2 meal type, compared to when the less palatable meal was offered in S2 (the b S1 b S2 condition)