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PMID: 42249138, DOI: 10.1038/s41591-026-04476-6.Peer-Reviewed Original ResearchAltmetricConceptsplacebo-controlled phase 2b trialglucagon-like peptide-1 receptor agonistsobesity treatmentpeptide-1 receptor agoniststreatment-related discontinuationsdouble-blind perioddrug-induced liver injuryphase 2b trialopen-label extensiondouble-blind studyGLP-1RA classdose interruptiontolerability profiledouble-blindPlacebo-Controlledgastrointestinal eventsGLP1-RAprimary endpointreceptor agonistsGLP-1RAliver injuryinterim analysisobesityLS meanweight loss 2637-P: Safety, Tolerability, and Efficacy of Aleniglipron in Doses up to 240 mg in People Living with Obesity: The Phase 2 ACCESS II Trial LINGVAY I, KUSHNER R, JASTREBOFF A , GERTSIK L, LIU M, CIVITARESE A, JU C, BUTCHER J, YUE H, BARTH A, COLL B
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